The medicine waste management started by the Junta in 1994 is characterised as having two clearly differentiated stages that coincide with the modification of the reference regulatory framework. Specifically, it was the approval of Law 11/1997 concerning packaging and packaging waste that caused the changes.

The Junta de Residus (now the Agència de Residus de Catalunya) in 1994, with the motto "Don't keep them. Give them", started the collection of medicines through the pharmacies and later the Primary Assistance Centres (CAP).

Those collected were managed by two entities, Farmacèutics Mundi (pharmacies) and Fundació Humanitària pel Tercer i Quart Món Doctor Trueta (CAPS), which through collaboration agreements with the Junta de Residus (now Agència de Residus de Catalunya) classified them into useful and useless, in order to contribute in charity campaigns with those who could use them and at the same time guarantee good management of the rest.

The second stage started in 2000 with the SIGRE system as a result of the mentioned packaging law and the WHO recommended that medicines from selective waste collection should not be given in donations or solidary campaigns, as their quality could not be guaranteed.

The current motto is We collect medicines for environmental health and the basic difference with respect to the previous stage is that the objective is no longer to use the medicines, but that they should all be correctly managed through installations evaluating recoverable packaging (paper, cardboard, glass, etc.) and the optimal disposal of the refuse that might remain.